99% Purity Min · CAS 77-78-1 · ISO 9001:2015

Industrial Dimethyl Sulfate Supply

RALA Prime Pvt Ltd supplies high-purity Dimethyl Sulfate (DMS) across India — 99%+ assay, UN-certified 200 Kg HDPE drums, complete COA & MSDS documentation for pharmaceutical, agrochemical, dye, and specialty chemical manufacturers.

99%
Minimum PurityMethylating Agent · UN 1595
Dimethyl Sulfate DMS
Dimethyl Sulfate — DMS
99% Purity Min UN 1595 · Class 6.1
(CH₃)₂SO₄
99%Minimum Purity
200 KgHDPE Drums / Bulk
7+Industries Served
ISO9001:2015 Certified
The Product

What is Dimethyl Sulfate (DMS)?

Dimethyl Sulfate (DMS) is a colourless to pale yellow oily liquid that functions as a powerful dialkylating agent — transferring methyl groups to oxygen, nitrogen, and sulfur nucleophiles with high selectivity and reaction efficiency across pharmaceutical, agrochemical, and specialty chemical sectors.

Its high purity (99% minimum), dual methyl equivalents per molecule, and favourable cost-to-performance ratio have established it as the standard methylating reagent for large-scale organic synthesis. RALA supplies DMS with complete COA, MSDS, and transport documentation dispatched with every order.

  • Pharmaceutical Synthesis
  • Agrochemical Manufacturing
  • Dye & Pigment Production
  • Surfactants & Detergents
  • Fragrance Chemicals
  • Specialty Chemical R&D
  • O-, N-, S-Methylation
  • Contract Manufacturing

Dimethyl Sulfate (DMS)

(CH₃)₂SO₄ · CAS No. 77-78-1
Purity99% Minimum
AppearanceColourless to Pale Yellow Liquid
Molecular Weight126.13 g/mol
Density @ 20°C1.33 g/cm³
Boiling Point188°C at 760 mmHg
Flash Point83°C (Closed Cup)
UN NumberUN 1595 · PG II · Class 6.1
Packaging200 Kg HDPE Drums / Bulk
Shelf Life12 months sealed at 15–25°C
CertificationISO 9001:2015 · GHS MSDS
Who We Serve

Industries We Serve

💊

Pharmaceuticals & API

N-methylation and O-methylation in antihistamines, antihypertensives, and defined API synthesis routes requiring high purity.

🌾

Agrochemicals

Methyl source in triazine herbicides, organophosphate intermediates, and carbamate compound synthesis at industrial scale.

🎨

Dyes & Pigments

N-methylation of amine precursors for cationic dyes — methyl violet, crystal violet, methylene blue — and reactive dyes.

🧴

Surfactants & Detergents

Quaternization of tertiary amines for fabric softeners, hair conditioners, antistatic agents, and industrial biocides.

🌸

Fragrance & Flavour

Selective esterification for methyl anthranilate, methyl salicylate, and methyl ionone aroma chemicals.

⚗️

Specialty Chemicals

Selective O-, N-, and S-methylation across fine chemicals, CROs, specialty producers, and industrial R&D operations.

🏭

Industrial Intermediates

Contract research and industrial chemical intermediates requiring dual methyl equivalents per molecule for atom economy.

🔬

Contract Manufacturing

Large-volume continuous manufacturing operations leveraging DMS's controllable reactivity and commercial availability.

Key Reactions

Product Applications

🔬

O-Methylation

Converts phenols, alcohols & carboxylic acids (-OH → -OCH₃) for pharmaceutical and fragrance intermediates.

⚗️

N-Methylation

Methylates primary and secondary amines to tertiary amines or quaternary ammonium salts for dyes and surfactants.

🧴

Quaternization

Converts tertiary amines to cationic surfactants — fabric softeners, biocides, and personal care actives.

🌱

Agrochemical Synthesis

Selective methyl transfer in herbicide and fungicide molecule production at commercial manufacturing scale.

💊

API Synthesis

Defined methylation steps in drug synthesis where 99%+ purity directly reduces downstream impurity burden.

🎨

Dye Intermediates

Cationic dye intermediate production delivering colour intensity, fixation rate, and wash fastness for textiles.

Why RALA Prime

Why Source DMS from Us

01
Consistent 99%+ Assay
Validated by titration on every production lot — reducing batch failures and simplifying downstream purification.
02
Complete Documentation as Standard
COA, MSDS, and transport declaration dispatched with every order — no additional requests needed, ever.
03
UN-Certified Packaging
200 Kg HDPE drums fully compliant with Indian and international hazardous goods transport regulations.
04
Buffer Stock for Regular Buyers
Dedicated inventory maintained year-round to prevent supply disruptions for repeat customers.
05
Export Capability
IMDG-compliant documentation, English MSDS, and customs support provided for international shipments.

Safety & Handling

⚠ Mandatory Precautions — UN 1595 · Class 6.1
Work exclusively in well-ventilated area or approved fume hood — vapour inhalation is acutely toxic
Wear butyl rubber / neoprene gloves, chemical splash goggles, and acid-resistant apron at all times
Prevent contact with water, alkalis, and strong oxidizers — reacts to release methanol and H₂SO₄
Store between 15–25°C in sealed containers away from heat, open flames, and moisture
CO₂ or dry chemical extinguishers only — water is not suitable for DMS fires
All buyers must comply with MSIHC Rules 1989 and maintain licensed storage facilities
Get in Touch

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